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The test which is used to check the integrity of packed strips, blisters, bottles and small sachets containing tablets, capsules and dry powders is called leak test. Whenever leakage observed during leak test, ensure that rectification is done. 1.2 leaks detected— this test method detects leaks in blister packs by measuring the deflection of the blister pack surface in response to an applied vacuum
This deflection of the blister pack surface results from the difference in pressure between the gas inside the blister pack and the applied vacuum. If there is machine break down more than 1/2 hour perform leak test immediately after starting the operation The next generation machine is built around our new 3d measurement technique to test the integrity of pharmaceutical blister packs.
The testing fixtures for blisters can also be applied in the testing for capsules or other small containers to enlarge the testing scope
At the same time, the testing for volatile pharmaceutical ingredients may refer to the testing methods for organic gas permeability rate. Standard operating procedure to determine the leak in strip and blister by leak test using leak test apparatus. Learn about the blister leak test usp, its role in pharmaceutical container closure integrity testing, and compliance with usp 1207 standard. Why is blister leak testing crucial in pharmaceutical packaging
Blister leak testing is vital because leaks can lead to moisture ingress, contamination, and compromised drug stability, ultimately affecting product efficacy and patient safety What is the vacuum decay method and why is it widely used for blister leak detection? Perform leak test at the starting of blistering / strip sealing, operation
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